Relate common adverse drug effects of current diabetes pharmacotherapy to key side effects that should be minimized based on national guidelines. People with type 1 diabetes must use insulin injections to keep their blood sugar at a normal or close to normal level. Formulate a patientcentered diabetes treatment plan. Discuss the new recommendations for antihyperglycemic therapy from the updated guidelines for type 2 diabetes. Abstract booklate breaking abstract handout new this year. The ominous octet washington association of diabetes. The types of diabetes are type 1, type 2, and a condition called gestational diabetes, which happens when pregnant. From harold himsworth to the insulin resistance syndrome. Keeping up with guidelines for treating type 2 diabetes mellitus to. The term prediabetes refers to subjects with impaired fasting glucose andor impaired glucose tolerance who are at increased risk for type 2 diabetes mellitus. Snack options what are some tips for healthy snacking. It focuses on the challenges and costs associated with diabetes care and explains how reimbursement strategies are evolving to demand a valuebased care system. Compare agents used in the treatment of dm, including mechanisms of.
Defronzo md professor of medicine and chief, diabetes division, the university of texas health science center at san antonio uthscsa, deputy director, texas diabetes institute, san antonio, tx, usa. Pharmacologic therapy for type 2 diabetes mellitus. People with type 2 diabetes often need to add insulin to control their blood sugar when oral medications or noninsulin injectable medications exenatide and liraglutide are not enough. Patient education handouts previously called patient education slicks the following are reproducible patient education handouts available in pdf format. This video is the first of a 2part series presented by drs. Recipes cook up something new in your kitchen with these resources for healthy, delicious recipes. Triplitt, pharmd, cde, muhammad abdulghani, md, and eugenio cersosimo, md novel agents for the treatment of type 2 diabetes from 1987 to the present, our understanding of the pathophysiology of type 2 diabetes has expanded from the triumvirate of. Defronzo1 diabetes care volume 40, august 2017 1121 pointcounterpoint. Find printable handouts and fact sheets that can be used for health fairs, classes, and other food or nutritionrelated events. Although current diabetes management focuses on lowering blood glucose, the goal of therapy should be to delay disease progression and eventual treatment failure. Noninsulindependent diabetes mellitus 23, treatment with troglitazone and acarbose. Learn, connect, engage american association of diabetes. Recent innovative treatment approaches target the multiple pathophysiological defects present in type 2 diabetes.
For many adults, eating 3 to 5 servings of carbohydrate foods at each meal and 1 or 2 carbohydrate servings for each snack works well. Ralph defronzo talks with diabetes in control publisher steve freed during the ada 77th scientific session in san diego about the major changes he has seen in diabetes treatment in the past 50 years. People with prediabetes have higher than normal bloodsugar levels but the levels are not high enough to have a diagnosis of diabetes. With the right treatment, you and your doctor can keep your kidneys working as long as possible. Living with type 2 diabetes di650105par what is diabetes. This creates ketones, which can make your blood acidic. Diabetes complications, comorbidities and related disorders. When you have type 1 diabetes, and do not have enough insulin in your body, you are at risk of getting diabetic ketoacidosis dka. It is well established that type 2 diabetes t2d is a complex metabolic. Your doctor will begin treatment based on the stage of. Supported by boehringer ingelheim pharmaceuticals, inc. Medical management of hyperglycemia in type 2 diabetes. Diagnostic criteria by the american diabetes association ada include the following. International textbook of diabetes mellitus pdf free download.
These handouts may be reproduced for educational purposes only through the expiration date with credit granted to ddpg. All five of these studies showed that, in addition to their insulin sensitizing. Insulin resistance in muscle and liver and impaired insulin secretion represent the core defects in type 2 diabetes 1. Multiple drugs in combination may be required to improve glucose homeostasis. Cdcs division of diabetes translation offers many fact sheets about diabetes. Compare the various noninsulin pharmacologic agents for the management of type 1 diabetes.
It means your blood glucose levels are higher than normal but arent high enough to be called diabetes. Pdf the american diabetes association, jdrf, the european. Materials and handouts consists of the participant schedule, tools to assist with tracking food, fitness, and weight, and additional resources. Nafld, nash and nontraditional associations with diabetes. The dream diabetes reduction assessment with ramipril and rosiglitazone medication study showed a 62% decrease in the development of type 2 diabetes with rosiglitazone, while the act now actos now for prevention of diabetes study showed a 81% reduction in the conversion of igt to type 2 diabetes with pioglitazone. Prediabetes is a condition that comes before diabetes. Diabetes mellitus is a major cause of morbidity and mortality in scotland and worldwide. Diabetes affects the way your body uses food most foods are broken down into glucose, a form of sugar in the blood insulin is needed to move glucose to all the cells in your body the pancreas makes and releases insulin when you eat. If your kidney disease is caused by diabetes, it is called diabetic kidney disease. There are many types of diabetes including type 1, type 2 and gestational diabetes.
Skip directly to site content skip directly to page options skip directly to az link centers for disease control and prevention. Table of contents 203 patient handouts in english and spanish chapter topic page 1. Novel agents for the treatment of type 2 diabetes ncbi nih. It is hard for the body to use carbohydrates and fats. At a glance 2018 diabetes and prediabetes fact sheet. The multiple complex pathophysiologic defects associated with type 2 diabetes mellitus require that multiple drugs be. The ominous octet outlined in orange are the three core pathophysiologies of type 2 diabetes, known as the triumvirate. Ralph defronzo, md is professor of medicine and chief of the diabetes division at the university of texas health diabetes center in san antonia. When there is not enough insulin, your body has to burn fat for energy. The canadian diabetes association is the registered owner of the name diabetes canada. Diabetes handouts for providers and educators scripps health. Identify current and emerging pharmacotherapy treatments for type 2 diabetes. We are supported in our efforts by a communitybased network of volunteers, employees, healthcare professionals, researchers and.
Although both types of patients are at increased risk for developing type 2 diabetes mellitus and cardiovascular disease, they manifest distinct metabolic abnormalities. Pathogenesis of type 2 diabetes mellitus international. Diabetes is a disease that affects how your body handles sugar glucose. In diabetes, the body does not use the food it digests well. A comprehensive handout with speaker information, ppt slides, and. Insulin resistance in muscle and liver and impaired insulin secretion represent the core defects in type 2 diabetes. In addition to the risk for diabetes, insulin resistance and impaired insulin secretion are.
How to help a loved one with diabetes when you live far apart pdf iconpdf 383k. Type 2 diabetes mellitus is a chronic metabolic disorder that results from. Clinical inertia in the treatment of type 2 diabetes mellitus is a. Describe the mechanism of action and unique features of the 6 classes of medications that are recommended by the ada as secondline therapies for type 2 diabetes. P atient handout overview 211 prediabetes according to the american diabetes association, before people develop type 2 diabetes, they almost always have prediabetes.
Ferrannini e, gastaldelli a, miyazaki y, matsuda m, mari a, defronzo ra. Is it time to change the type 2 diabetes treatment. This will require you to create an account if you dont already have one. Diabetes can also be caused by certain medicine including steroids, chemotherapy and others. Pdf differentiation of diabetes by pathophysiology, natural. If you have diabetes, your body either doesnt make enough insulin, it cant use the insulin it does make very well, or both. Below is the complete table of contents offered inside international textbook of diabetes mellitus pdf. For example, if your lunch break is at noon, but you dont get home. Advancements in individualizing treatment for type 2 diabetes. This resource, available in both webbased and pdf versions, was developed by a group of people with diabetes and diabetes educators.
Dpac diabetes patient advocacy coalition ndvlc national diabetes volunteer leadership council most u. Cv im awesome foursome pdf by ben brown md thanks to steven sinatra md date. Type 2 diabetes nutrition therapy page 3 meal planning tips a meal plan tells you how many carbohydrate servings to eat at your meals and snacks. Integrative medicine for the underserved a nonprofit organization we are affiliated with. Bring glp1 activity into the conversation early1 discover a. The programs on this page are not for use by organizations or health care professionals. Identify differences between prediabetes, type 1 diabetes mellitus t1dm, type 2 dm t2dm, and gestational diabetes gdm, including differences in diagnostic criteria and clinical presentation. The handouts are to be given to participants working with coaches in lifestyle change programs. Skip directly to site content skip directly to page options skip directly to az link centers for disease control. Defronzo ra, hissa mn, garber aj, gross jl, duan ry. Uptodate information on the interactions between diabetes and a variety of comorbid.
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